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Off-site T-cells Links, User Submitted

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Wed Jun 24

• HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation : Abstract : Nature Medicine: HIV persists in a reservoir of latently infected CD4+ T cells in individuals treated with highly active antiretroviral therapy (HAART). Here we identify central memory (TCM) and transitional memory (TTM) CD4+ T cells as the major cellular reservoirs for HIV and find that viral persistence is ensured by two different mechanisms. HIV primarily persists in TCM cells in subjects showing reconstitution of the CD4+ compartment upon HAART.

Mon Jun 15

• Carbon nanotubes may suppress immunity: Inhaling carbon nanotubes can suppress the immune system, according to scientists. The findings raise possible health concerns for those working in the manufacture of the materials.

Tue May 19

• Home of immune memory found :The Scientist [7th May 2009]

Fri May 8

• Natural killer T cells regulate the development of asthma

Tue Apr 21

• Genetically engineered immune cells may have helped two patients with advanced prostate cancer to fight the disease, preliminary results suggest. | nature news: Prostate cancer kills more than 28,000 men in the United States alone each year. Although many patients have their prostate glands removed, the cancer can spread rapidly to other parts of the body, usually the bones. Current drug treatments, such as male hormone suppression therapy, often fail after just a few months. The researchers extracted a type of white blood cell called T lymphocytes, or T cells, from the patients, who had already had their prostate gland removed. These cells normally fight infections, but the researchers used a virus to insert genes into the cells that would help them to target any remaining prostate cells. The modified cells were then injected back into the patients.

Thu Apr 16

• Regulatory T cell - Wikipedia, the free encyclopedia: Regulatory T cells (sometimes known as suppressor T cells) are a specialized subpopulation of T cells that act to suppress activation of the immune system and thereby maintain immune system homeostasis and tolerance to self-antigens. The existence of a dedicated population of suppressive T cells was the subject of significant controversy among immunologists for many years. However, recent advances in the molecular characterizati on of this cell population have firmly established their existence and their critical role in the vertebrate immune system. Interest in regulatory T cells has been heightened by evidence from experimental mouse models demonstrating that the immunosuppress ive potential of these cells can be harnessed therapeuticall y to treat autoimmune diseases and facilitate transplantatio n tolerance or specifically eliminated to potentiate cancer immunotherapy.
• Cytotoxic T cell - Wikipedia, the free encyclopedia: A cytotoxic T cell (also known as TC, CTL, T-Killer cell, cytolytic T cell, CD8 T-cells or killer T cell) belongs to a sub-group of T lymphocytes (a type of white blood cell) that are capable of inducing the death of infected somatic or tumor cells

Mon Apr 13

• Beta Glucan Research: Beta glucan is a scientifically proven biological defense modifier (BDM) that nutritionally potentiates and modulates the immune response. As a supplement, after swallowing orally, Beta glucan is ingested primarily through macrophage and dendritic immune cells, to nutritionally and safely yield, through immune response potentiation and modulation, in many instances various therapeutic healing effects generated by the immune cells.  For many years Glucans have been investigated (History) for these immune enhancing properties, particularly their ability to activate macrophage immune cells and NK-Cells, plus in turn, the T-Cells, and B-Cells including selected cytokines and complement. 

Fri Apr 10

• Special regulatory T cell review: The resurgence of the concept of contrasuppress ion in immunoregulati on. - Immunology. 2008 Jan: Special regulatory T cell review: The resurgence of the concept of contrasuppress ion in immunoregulati on. Lehner T. Immunology. 2008 Jan

Wed Mar 25

• T cell-mediated immunoregulati on in the gastrointestin al tract

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